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I used to do a lot of digital pre-press when I was a graphic designer for a retail chain and I had to prepare work to be printed in a multitude of formats (newpaper, magazine, poster, etc.) and - except for maybe two or three very special cases) I always worked at 600 dpi and then knocked files down...

Well, I realize I am replying to this thread a little late, but I just joined the board after reading Scott McCloud's books back-back (if you are reading this Scott, they were the best reads I've had in a long time!!! very thought provoking). Anyhew, here's my two cents: On the issue of file size, I...