I'm not much further ahead than you are Yingo, but I will toss my hat in just the same. I am facing some of the same questions right now, as I begin to put my first webcomic together, and though I am probably doing everything ass-backwards, you can look at me as a work in progress, if you'd like.
I decided that I might be interested in doing a comic about a year ago, and started sketching furiously, waiting for the right idea to come along. I filled three sketchbooks with character sketches until I fell upon the characters I am now using, and the basic back-story. Even then, it took me until just over a month ago to decide on a whim that I should do it as soon as possible.
I looked at investing in a domain name, and web-hosting, planning to avoid the whole Keenspace thing, but realized that I had never done this before, and before I invested any significant amount of money I should prove to myself that I can produce a regular comic, so I signed up on Keen, and now have my own site:
http://japanimationfist.keenspace.com - There isn't much there for the moment, but I am putting it together and hoping to launch it at the end of the month.
I am still planning to invest in a domain name (in July?) that I can use to bounce people to my Keenspace site, but I am putting off the larger investment until I've put about a year in, so I can decide if I am serious enough to keep this up. Ideally I would have built everything from scratch, and had it hosted somewhere without becoming one of the nameless Keeners, but this is cheaper for now, and will give me a good place to cut my teeth.
As for the actual construction of the web-pages, Keenspace has a number of tutorials, and they have a system of "tags" to help you add functions to your page. It's almost idiot-proof, but it's also a little restrictive. You have to have the banner ad at the top of your page, and you're somewhat limited as to how you can construct your archive pages. I would have prefered to do something a little more experimental, but once again, this will do for the moment.
For the moment I am using Adobe Pagemill, which came with my Mac when I bought it. It is a simple html editor, which offers you the option of switching back and forth between source code, and layout view. It was free, and I am learning html as I go because I am able to construct things like tables and links, and see what they look like in code. I have some friends who swear by hand-coding, and tell me that I am taking the lazy way out, but to be honest, I am just starting on the comic, and I want that to be my focus, not html. I am hoping that I will learn html as I go, though I would eventually like to move on to Dreamweaver.
As for art, I am currently using Freehand to do the actual illustration work, and then Fireworks to export the files for the web. I would love to have a tablet to draw on, but the government recalculated my income tax, and I got shafted, so I will have to wait another few months. In the meantime I am doing all my drawin with the mouse. Not easy, I'll admit, but I like the challenge, and I figure that when I finally get a tablet it will be easy as sin.
So, there you go, my two cents. You can tune in from time to time over the next few weeks, and watch me struggle with my tools, and then make a point of not doing everything I do wrong, and you will probably do just fine.
P.S. There are no comics on my site, as yet, but I wouldn't mind some comments or critiques on the general layout right now. I am trying to tweak it day by day, so that it will be ready for June 24th. Be gentle. This is my first time.