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The data discussed in this publication have been deposited in NCBI's Gene Expression cheap rs 3 gold Omnibus and are accessible through GEO Series accession number GSE63569.Top of pageResultsSF3B1 knockdown inhibits cell growth, induces cell cycle arrest and impairs erythroid differentiationSF3B1 was knocked down using siRNA technology in four myeloid cell lines (TF1, K562, HEL and SKM1) that we found to be wild type for SF3B1 (Supplementary Information), resulting in a significant decrease in expression ranging between 50 and 60 (Figure 1a). Each cell line transfected with siRNA targeting SF3B1 was compared with the corresponding cell line transfected with the scramble control. (a) SF3B1 mRNA expression measured 3 days after knockdown.
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